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About the Laboratory
The Dendritic Cell Research group (DCR) is directed by Professor Derek Hart. They discover key immune markers and biological processes which will provide new diagnostic and therapeutic products for improving patient care.
The group studies DC surface molecules to determine how these molecules influence DC function and how antibodies targeting them might be used in clinical practice. A major part of our work is aimed at using the patient’s immune responses to treat haematological cancers.
We are testing our findings in preclinical models of stem cell transplantation, leukaemia, multiple myeloma, prostate cancer and other malignancies.
We are striving to develop novel immunosuppressive strategies, including our previous anti-CD83 antibody as a novel therapeutic agent. We aim to use this antibody to improve transplant outcomes, whilst preserving the patient’s ability to fight infections and cancer. Negotiations to support a clinical trial of anti-CD83 in allogeneic haematopoietic stem cell transplantation are underway.
Latest News and Events
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DC Down Under Symposium 2016 – Now Approaching
dc-down-under-final-program. To register, complete the dc-down-under-2016-registration-form and return via email to dcr.admin@sydney.edu.au
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2015 – What a Year for DCR!
2015 has been a great year for Dendritic Cell Research. DC Down Under 2015 was another great success. With...
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Stuck on what to buy your colleague this Christmas for Kris Kringle?
When you have only $10 or $20 to spend, it can sometimes be difficult to find a gift which...
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Dendritic Cell Image for all to see
This is an image of a dendritic cell taken at 100x magnification. Dendritic cells are specialised cells in the...
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New clinical antibody created using the science of gene cloning
Dendritic Cell Research Publish Landmark Paper Dendritic Cell Research (DCR) has a major interest in Dendritic Cell (DC)...
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Dreadlocks anyone?
Cristian Silveira donates money raised to Dendritic Cell Research Cristian Silveira had been growing his hair for about 17...
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Gardens, Transplants and Collaborations
Dr Xinsheng Ju talks about his recent attendance at the 2015 Transplantation Science Symposium (TSS 2015) TSS 2015 was...
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The cell treatment changing the lives of those living with Glioblastoma
Professor Derek Hart leading Australian research in Dendritic Immunotherapy. Broadcast on Today Tonight Thursday 1 October 2015.
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John’s Multiple Myeloma Story
Featured in MyeNews, Spring Issue, 2015. John Fullagar gave the consumers perspective at the recent DC Down Under Symposium DC...
About Our People
Professor Derek Hart
Prof Hart has made major scientific and clinical contributions, particularly in relation to his special interest in dendritic cells (DC), immunotherapy and BMT. He is a Rhodes Scholar and RCPA Distinguished Fellow Prof Hart directed the Christchurch Clinical Haematology Unit and BMT Unit and left it with a significant research reputation, including UK MRC trial participation…..read more
Associate Professor Georgina Clark
Associate Professor Georgina Clark completer her PhD in molecular immunology at the University of Melbourne. She continued her studies in leucocyte surface molecules undertaking postdoctoral work at the University of Oxford, UK and the University of Otago, New Zealand where she joined Professor Hart’s group studying the molecules found on the surface of dendritic cells…..read more
Dr Pablo Silveira
Dr Silveira was awarded his PhD from the University of Sydney for research analysing the genetic mechanisms conferring susceptibility to autoimmune gastritis…..read more
Dr Xinsheng Ju
Dr Xinsheng Ju studied medicine for six years and received another three year medical science training in China, then he moved back to clinic as a haematologist… read more
Dr Phillip Fromm
Dr Phillip Fromm completed a PhD in cellular immunology elucidating the role of tumor necrosis factor and its receptors in the development of dendritic cells…..read more
Our Research Specialities
Dendritic Cell Research
The ANZAC Research Institute
Concord Repatriation General Hospital
Gate 3, Hospital Road
Concord NSW 2139, Australia
P: +61 2 9767 9100
F: +61 2 9767 9101
E: dcr.admin@sydney.edu.au
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