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About the Laboratory
The Dendritic Cell Research group (DCR) is directed by Professor Derek Hart. They discover key immune markers and biological processes which will provide new diagnostic and therapeutic products for improving patient care.
The group studies DC surface molecules to determine how these molecules influence DC function and how antibodies targeting them might be used in clinical practice. A major part of our work is aimed at using the patient’s immune responses to treat haematological cancers.
We are testing our findings in preclinical models of stem cell transplantation, leukaemia, multiple myeloma, prostate cancer and other malignancies.
We are striving to develop novel immunosuppressive strategies, including our previous anti-CD83 antibody as a novel therapeutic agent. We aim to use this antibody to improve transplant outcomes, whilst preserving the patient’s ability to fight infections and cancer. Negotiations to support a clinical trial of anti-CD83 in allogeneic haematopoietic stem cell transplantation are underway.
Latest News and Events
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Dr Silveira presents at The Transplantation Society Conference
On my way to The Transplantation Society (TTS) conference in Spain, I stopped off in Oxford UK, where I...
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August 2018 Events Registration Form
If you would like to register for one or all of the following events; Wednesday 8 August 2018 Professor...
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DC Down Under Symposium 2018 Final Program & Registration
This year we are holding the DC Down Under Symposium for one day – Thursday 9 August 2018...
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Save the Dates
Celebration of the late Professor Derek Hart’s Contribution to Immune Therapies Date: Wednesday 8th August 2018 Time: starting at 5.30pm...
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DC Down Under Symposium 2017 Program & Registration Form
Select either the program or registration form below. FINAL DC Down Under Symposium 2017 Program DC Down Under Symposium...
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DC Down Under Symposium 2016 – Now Approaching
dc-down-under-final-program. To register, complete the dc-down-under-2016-registration-form and return via email to dcr.admin@sydney.edu.au
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2015 – What a Year for DCR!
2015 has been a great year for Dendritic Cell Research. DC Down Under 2015 was another great success. With...
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Stuck on what to buy your colleague this Christmas for Kris Kringle?
When you have only $10 or $20 to spend, it can sometimes be difficult to find a gift which...
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Dendritic Cell Image for all to see
This is an image of a dendritic cell taken at 100x magnification. Dendritic cells are specialised cells in the...
About Our People
Professor Derek Hart
Prof Hart has made major scientific and clinical contributions, particularly in relation to his special interest in dendritic cells (DC), immunotherapy and BMT. He is a Rhodes Scholar and RCPA Distinguished Fellow Prof Hart directed the Christchurch Clinical Haematology Unit and BMT Unit and left it with a significant research reputation, including UK MRC trial participation…..read more
Associate Professor Georgina Clark
Associate Professor Georgina Clark completer her PhD in molecular immunology at the University of Melbourne. She continued her studies in leucocyte surface molecules undertaking postdoctoral work at the University of Oxford, UK and the University of Otago, New Zealand where she joined Professor Hart’s group studying the molecules found on the surface of dendritic cells…..read more
Dr Pablo Silveira
Dr Silveira was awarded his PhD from the University of Sydney for research analysing the genetic mechanisms conferring susceptibility to autoimmune gastritis…..read more
Dr Xinsheng Ju
Dr Xinsheng Ju studied medicine for six years and received another three year medical science training in China, then he moved back to clinic as a haematologist… read more
Our Research Specialities
Dendritic Cell Research
The ANZAC Research Institute
Concord Repatriation General Hospital
Gate 3, Hospital Road
Concord NSW 2139, Australia
P: +61 2 9767 9100
F: +61 2 9767 9101
E: dcr.admin@sydney.edu.au
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