The group studies DC surface molecules to determine how these molecules influence DC function and how antibodies targeting them might be used in clinical practice. A major part of our work is aimed at using the patient’s immune responses to treat haematological cancers.
We are testing our findings in preclinical models of stem cell transplantation, leukaemia, multiple myeloma, prostate cancer and other malignancies.
We are striving to develop novel immunosuppressive strategies, including our previous anti-CD83 antibody as a novel therapeutic agent. We aim to use this antibody to improve transplant outcomes, whilst preserving the patient’s ability to fight infections and cancer. Negotiations to support a clinical trial of anti-CD83 in allogeneic haematopoietic stem cell transplantation are underway.
Latest News and Events
View the DC Down Under Symposium 2019 Program here
Download, complete registration form and return to firstname.lastname@example.org by Friday 26 July 2019
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2015 has been a great year for Dendritic Cell Research. DC Down Under 2015 was another great success. With...
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Dendritic Cell Research Publish Landmark Paper Dendritic Cell Research (DCR) has a major interest in Dendritic Cell (DC)...
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Dr Xinsheng Ju talks about his recent attendance at the 2015 Transplantation Science Symposium (TSS 2015) TSS 2015 was...
About Our People
Professor Derek Hart
Prof Hart has made major scientific and clinical contributions, particularly in relation to his special interest in dendritic cells (DC), immunotherapy and BMT. He is a Rhodes Scholar and RCPA Distinguished Fellow Prof Hart directed the Christchurch Clinical Haematology Unit and BMT Unit and left it with a significant research reputation, including UK MRC trial participation…..read more
Associate Professor Georgina Clark
Associate Professor Georgina Clark completer her PhD in molecular immunology at the University of Melbourne. She continued her studies in leucocyte surface molecules undertaking postdoctoral work at the University of Oxford, UK and the University of Otago, New Zealand where she joined Professor Hart’s group studying the molecules found on the surface of dendritic cells…..read more
Our Research Specialities
Dendritic Cell Research
The ANZAC Research Institute
Concord Repatriation General Hospital
Gate 3, Hospital Road
Concord NSW 2139, Australia
P: +61 2 9767 9100
F: +61 2 9767 9101
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